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When signs do occur, they typically appear as one or more blisters on or around the genitals or rectum.

Some of these viruses are called "high-risk" types, and may cause abnormal Pap tests.

They may also lead to cancer of the cervix, vulva, vagina, anus, or penis.

Typically, another outbreak can appear weeks or months after the first, but it almost always is less severe and shorter than the first outbreak.

Although the infection can stay in the body indefinitely, the number of outbreaks tends to decrease over a period of years. Results of a nationally representative study show that genital herpes infection is common in the United States.

About 6.2 million Americans get a new genital HPV infection each year. The types of HPV that infect the genital area are spread primarily through genital contact.

Most HPV infections have no signs or symptoms; therefore, most infected persons are unaware they are infected, yet they can transmit the virus to a sex partner.

At least 50 percent of sexually active men and women acquire genital HPV infection at some point in their lives.

By age 50, at least 80 percent of women will have acquired genital HPV infection.

Nationwide, at least 45 million people ages 12 and older, or one out of five adolescents and adults, have had genital HSV infection.

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